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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad95ad724066c8009f35a311f11361d4ed04a78c60fb1e4a88e60ad32198dd78' 
  AND token = 'fwCnvb4WiFc/GIN5GVVEPUe5Dv4X/5LYLxRAEnzcnLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}