SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1da32f4a89cb4852a068fefaba9d5ef162a00be10175bfb30475182244f5a35b' 
  AND token = '4Paar+XFkf4S38MmCbJYnOu80M8nD1lj0CgDIc44Diw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}