SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f732f2f5be89a30d9f90ef93c8c1d04f81ccffc0edf5f5aec502b752425aeed8' 
  AND token = 'I1UEnGsJR9zrM1wX4v44VLbukweLMDg1LeYy9Yr3C6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}