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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b27ecd5ee79581a675f0159e78872d4c6579a636594b521f9445f540058a467d' 
  AND token = 'zb5xOtPKvT0fneOse3zHcOafDq3640YPE6CvNXRtyfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}