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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85ad85cf7c4d614e5b301f7ac14206203f7f975ba7ef93ad1bbd945bb6c3a426' 
  AND token = 'Yk3NB+x4Iy+hei4oInQABiu+v2/kyWUPQrOTwqbXqO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}