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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cb426dcf332e261dcb05379a3a7b287f6c8f2a8d0417d2bb0c4a676e62d8589' 
  AND token = 'Tdx85yQDXEmOY9M3XOu/KD/7jww235Z+ZfLDPSlqR7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}