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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c43641acb1d2fba328871e56fdc2708007fd2e60125731ae3937afeca726cc6a' 
  AND token = 'Y0+fpEWK1aN0/38WnrGXdABxll72LLA7zFxn5/1bf8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}