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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fb35bf0136a360dd2eac31041f6ccca19884209bbb695c201e28e107e5050b3' 
  AND token = '/I3EZLGjS5MbQnAm7x5A+nhmuvOfx35FPZG3FBHZNk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}