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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d59c14875206e6872d103b2d6a5a8105102863c127b1e834b4db5a1616c6871' 
  AND token = 'Y+PRUKKzqDnkx6LnMxT92XjmiXAW1YfzeFL09i98oDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}