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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8042968c77801527d8b55bb16887561989dec7bc8141ce800cf86be3b2aa1dc8' 
  AND token = 'JeF8iAKVAAR04l5Q+QfsiIUSLe7SFzePb3qtxzKA9vA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}