SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b0723f3612e09a495155150fc6596b4537ff544b11e51d4c65de372c44f0352' 
  AND token = 'CwXXJJpSAtRSvj3s99/3LNRdMqFmUmHtS3s+qpah/Tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}