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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e14045c90eb42e61a641bef1c5cfbcbe18431be2c37cdfa565c52ae69a5fc36b' 
  AND token = 't5A8hhLb8YrLHKFyrN3snKD4Bx91yePGYZm2QAviWMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}