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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a5c9dc37b91f115a921acb5a0e5fa0377a5e3066eb139f25a5c1112920b23ed' 
  AND token = '111ooPgtzibYh3uZtVpsnbe20tQeFzQsqxHfDasuhtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}