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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a416d3a95984796c6d16b2c459f212355e77e38d5993658764c9f65e8e2c4fb' 
  AND token = 'etHsYS9SdWtH5fIq/sq6c9EGkntGwqLQMPF1Sv6nPNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}