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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77f49b379199110a6ab995ad568db97fe4ae62510984019f866025ced00a63df' 
  AND token = 'KOog67BDtOS4tNDBOq/lClfZhnHE49WIrlaAvNBhPCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}