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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ea5a212067878af775464b20437d1223c565e2f9b7a2b5cc77c60fb23c69036' 
  AND token = 'UKyi+0faN1S95mrk3MFJtWZQKENtTizEYp/0OhcZLMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}