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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0468be2e85cd447af9fc11444fd0297aae5ea91009f71c6f78e75d635bf421fb' 
  AND token = '1XZYV9lVxurOoSjAHPC/KjlvEkRRb1tVR3nYVbRY5rA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}