SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5e3e27bad8ffaa7c1682f99c257ba7a19d3e12611d3fe7d2683274eee51b029' 
  AND token = 'syQq4oA8LLYb3JyAzawqODFR2x3cOQMJ2E6hcj8znso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}