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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb48da6aceb5e97230a4c348a6dacad36fe36e853e352f55ace7cd50e4cdd62f' 
  AND token = 'DEaqj6GIqiaJhgtVb3c/J19n+Frla+Ni0Nuve+DsXuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}