SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '300bac4bdafafee6f978dd598aad38d50c56be56f83281bb2000d625fff7c051' 
  AND token = 'zk1GuEI24qIQ6wYJC7mJdQgMdA/KKZetNQwlpaltbJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}