SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53eaa57dd506cee6e20e4f7d90dbaa7873b6b413139138e1c5a5c228b12a8386' 
  AND token = '38yuWiTeMsJ7Pck+0Qb3YKs0uj7w+NxLOAMwsMzx6og=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}