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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2c55aeabeeab0934613f5eb252a78b701a5b516bb81c02ac0f9bf82d379f218' 
  AND token = 'ZJ5LAipN3lIZ4HqwlaHyW7D752Is7GewAI52khzfkqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}