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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d45802580059cb2fe14ec9a877af80d0cb242a269eb4dfe9fde15e6e08b6885' 
  AND token = 'yy0pXFU/An0gwWBa/7hiD5jxXDIsj+8atgGG+QpKHU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}