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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '604ab50407cf2d6a0bdd1cd1432a51d3959cb9139375e91362dc723f115c29d6' 
  AND token = 'YBMmSA/G97K8F2iwlbNg7LDjyFAEkUapu3AA4v7wQ8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}