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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '624debb63f3a3c76206c51d071a9f7c6667b7574c75dd4d1fe69a423abd515af' 
  AND token = '0bsWdUf5QLmSsGW6fIbSW+EfXAEuVy4M+UfdkFD46GM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}