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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59492b30f5c627760b118bef922812950260cf5f95698ffd802c2177cf416519' 
  AND token = 'ItNdl8s2fwqWp0I83xVfuCTLGc/dmW61umavrelrGIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}