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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0c904311e6f290d1af98d0e5edbf1d301478d0189c100a4ab93269243d0cc00' 
  AND token = '+FmSSAXtj6PCAMnUigBAteyT31BZwksCuSpCscrGHMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}