SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04b03a898d506551cba2a1ad6ddab1f9416d601d5b59fe7972e2201686be6325' 
  AND token = 'G440P0KriBY5kNc4haIOFoXC8GubqftQ+UeFGpfr3Zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}