SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '323f0a39f6c0824f881d302b83648f26ec3983b5c35833b199489db6ddd35588' 
  AND token = 'N3MLkT8Lh7z7Lg2/7AvVJrCc2MheSWzj5VDzHwF1dRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}