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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc943c5a1586b734fe907c3b67e203761c3d8a288a5aa87237a5ec2da326c1ee' 
  AND token = 'KPGBN4eD8PrpM6a2n2pd+0t/pKPXYtdxhoe060D4Bzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}