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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c50b2c076d9d98066b6135866193e4b8c7ee907ed7f6224940b77bb11d3c84bb' 
  AND token = 'hxF4cAHSunEgTGdZgAOkDKJYjKaNZKpdPoy8yFM6qpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}