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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74b4a9e4051ca39ced3978848c48dcf5092c5685d93f944deee15170e4b7e0bc' 
  AND token = '1mBdsOu3VIIO5zjOqQHaTAsAGGbsuHDcwt9oOk6BUn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}