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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d8360b7e3c6468a06a8a1b2762d78c3f28c3f9d4f7e4aa34bf54c9fe23e99c3' 
  AND token = 'dmNfeSKnRKsI4TL2oYma/KzD697rItkXc0h0JaSgRWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}