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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abca50978913174da2fc87035c5264c52e780e8a1c66152281a056c0bcf78dd2' 
  AND token = '1lRTpF/GFJhORVzrsnb5GaoOHVmG9KCVrEi+Es4U6mU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}