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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '324e86106f14e249e7df325f58e0258aaba0e7807fe40685f9ea2bbe7cae457f' 
  AND token = '4B5zrWpiReO7slXL65jyUEZnMNa5M4diwJ1c/wfGqG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}