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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '099eb0c6d639f8178a0e8fe8f1e16fb3cff99cf2af50877aac8dfa1e2f2b0ab2' 
  AND token = 'lQPjjbW+ZdwJybbTsRc7jdwSXFYqD3TgGZ5QYBMdfNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}