SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c72504f3aec90a2272f70f4da30cfbe4705d70cd833fb182720841e552c6d90' 
  AND token = 'nTBvWLGwmbK4j2tJ39XFU7rOqRMwyu1gP0TIvtRcWgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}