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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95c6fbc2d83d2baec7196acd728f2cda8bf37486a15a070cc98f78b0dcf15b46' 
  AND token = '4yq7Xu/1KFAKeUyXkb0ESg/V6KSnxfvhYWy0CAWBE9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}