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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54cd371d2f8131dd74fe276930aa6b0257e977f2764e2644ee71e1f2ff74f32d' 
  AND token = 'zv2o2AYHt6agbkNaKy2Nb0NmkY7yd8/FI0P3ctjRmiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}