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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '735ef19f006b7036960a154e9523af29c5bda8db54ff4f08411b3e20a793900f' 
  AND token = '5NsT7siwQcLyUztFRbj6LCKUiT7ToCJuzPTWrund9XI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}