SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a746ea8781133ffc4a95814ee2cdb3d9e4e0b05355b06d182d324cd43bce9c13' 
  AND token = 'EwA/0gdtuIJk+qAbPLPRovY0XoxCcEadNCwhyJ5a4yE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}