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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '534881f6dbdb0ce48e9bef8b92b71ac7bf2a89f32ed7100338b21dd5c0ff06b0' 
  AND token = 'CmmiLIDVO1ARyfWk0DnIDkYcqvmGN4SkW4dLVG82Dyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}