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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c81269daac8850df57c74180734dbe959f15074cd7c60c2054677f422a0e3a41' 
  AND token = 'j700PkTaL/YO46tIIrhaMbC5u4CT2GzbF/vUTH4spbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}