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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2472feb2080fe8691e6a87657a1bd9abc506c3de2099e37bebca8d0623a7b266' 
  AND token = 'eBa1oqPQ0UAm34UwGrYPiBdfpXz23CFQgqD4iNgDLO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}