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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '053fb5f5795f66180a615759b5176ca5a01f9b6c64f7f5e97d7b3001963ee0f8' 
  AND token = 'giMq3H9555XOVeVzz8GvAzK7Yk4/ipGn7VGGIekm7xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}