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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1b3e3268039059446414b30841a7a376f948f9911efa14b6ced073efe65e4a0' 
  AND token = 'PWJ7FRNHgGKmybmC6JK/alZQyCKncMCd1f5DEqqVEaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}