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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '727b617172d85f6e8f2e9abbe085e2cfb458ed7f285d28d2f285d0349d1d1027' 
  AND token = 'WN3r5WDOmaHVE/5Alfpieuw96rFHZUir77LR/lZsgEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}