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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f61aafe987ecda8ea9f5431f1930281fd72bd85d7b3e32166bc041b6779c7756' 
  AND token = 'a8N/9m7xOGuVxuQ5p7Q+ORpDRHKm+2SUFuFmiRH4k54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}