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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3000d7262123389f6fe05eeb61cb14c902e5a6c0f4f66472a32b394d1b30c367' 
  AND token = 'W+Gkn/5feoWbMcjSVNRrnu7P2W7Jr1S683SNABcywaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}