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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '160c36a9b3f1148b90be19b2a60ae4b5fa00c462d3e69205ea1e174470a5e86a' 
  AND token = 'MlftDs0Rpmj2O7IoXMIU4uiKmHevPuS/nfMMhhl2Fi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}